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Borrelia & Leptospira Species

The syndrome of relapsing fever consists of two clinical entities: epidemic relapsing fever caused by Borrelia recurrentis (LBRF) and transmitted by the human body louse and endemic relapsing fever caused by Borrelia spp. (TBRF) and transmitted by arthropods (Table 1). A. Epidemiology. 1. Louse-borne epidemic relapsing fever (LBRF).

Nocardia

Nocardia spp. are strictly aerobic, ubiquitous soil-dwelling organisms that are largely responsible for the decomposition of organic plant material. Infection usually occurs via inhalation of these organisms in airborne dust particles, leading to pulmonary disease.

Brucella, Francisella, Pasteurella, Yersinia, & Hacek

Brucellosis (also called undulant fever, Mediterranean fever, Malta fever) is an infection that causes abortion in domestic animals. It is caused by one of six species of Brucella coccobacilli. It may occasionally be transmitted to humans, in whom the disease could be acute or chronic with ongoing fever and constitutional symptoms without localized findings.

Pasteurella

Pasteurella multocida has been recovered from cultures of specimens from the nasopharynx and the gastrointestinal tract of a large number of asymptomatic wild and domestic animals. The highest carriage rates occur in cats (50%-90%), dogs or swine (50%), and rats (15%). Infections are usually preceded by a cat or dog bite or scratch on an extremity.

Important Anaerobes

Anaerobic bacteria are the predominant component of the normal microbial flora of the human body. The following sites harbor the vast majority of them:

Toxin-Mediated Infections

Tetanus is a disease of global incidence produced by the toxin of Clostridium tetani. The risk of acquiring it increases in people > 60 years of age and in neonates, especially in Third World countries where poor sanitary conditions predispose to umbilical stump contamination. Immunization campaigns have played a crucial role in bringing about the observed decreasing incidence in the United States. The pathogenesis of tetanus involves the absorption of preformed toxin, or, less commonly, invasion of toxin-producing organisms from contaminated wounds; it may complicate surgical wounds colonized with C tetani.

Haemophilus, Bordetella, & Branhamella Species

Before 1990, strains of Haemophilus influenzae type b were found in the upper respiratory tract of 3-5% of children and a small percentage of adults. Colonization rates with type-b strains are even lower now, reflecting routine immunization of infants against H influenzae type b. Non-type-b encapsulated H influenzae are present in the nasopharynx of < 2% of individuals, whereas nonencapsulated (nontypable [see below]) strains colonize the respiratory tract of 40-80% of children and adults.

Branhamella Catarrhalis: Clinical Syndromes

B catarrhalis causes bronchitis and pneumonia in patients with underlying lung disease, especially chronic obstructive pulmonary disease. It is also a rare cause of invasive disease, including meningitis, endocarditis, bacteremia without a focus, septic arthritis, and cellulitis.

Haemophilus Influenzae: Clinical Syndromes

H influenzae was first isolated during the 1892 influenza pandemic and was originally believed to be the causative agent of influenza. Although subsequent studies revealed the fallacy of this idea, H influenzae has proved to be a common cause of localized respiratory tract and systemic disease, including meningitis, epiglottitis, pneumonia, pyogenic arthritis, cellulitis, otitis media, and sinusitis, among others (Box 1). Meningitis is the most common and serious form of invasive H influenzae type-b disease. In the mid-1980s, before the introduction of effective vaccines, ~ 10,000-12,000 cases of H influenzae type-b meningitis occurred in the United States each year, and 95% of cases involved children < 5 years old.

Helicobacter Pylori

Pathologists have noted spiral bacteria in biopsies and autopsy specimens of gastric mucosa for over 100 years. Their significance was alternately debated and ignored until 1982, when Barry Marshall and Robin Warren cultivated the organism for the first time and suggested that it might be a cause of chronic gastritis and peptic ulcer disease. Although initially called Campylobacter pylori, subsequent taxonomic studies showed that the bacterium was not a true Campylobacter species, and it was renamed Helicobacter pylori.

Dosage forms of Amoxicillin:
Amoxil 400 mg Chew Tabs Amoxil 875 mg tablet Amoxil 200 mg/5ml Suspension 100ml Bottle Trimox 125 mg/5ml Suspension 100ml Bottle
Trimox 125 mg/5ml Suspension 150ml Bottle Trimox 250 mg/5ml Suspension 80ml Bottle Amoxil 250 mg/5ml Suspension 100ml Bottle Amoxil 250 mg/5ml Suspension 150ml Bottle
Amoxil 50 mg/ml Suspension 30ml Bottle Amoxicillin 250 mg/5ml Suspension 150ml Bottle Amoxil 400 mg/5ml Suspension 50ml Bottle Amoxicillin 400 mg/5ml Suspension 100ml Bottle
Amoxil 400 mg/5ml Suspension 75ml Bottle Amoxil 400 mg/5ml Suspension 100ml Bottle Apo-Amoxi 25 mg/ml Suspension Novamoxin 25 mg/ml Suspension
Novamoxin Sugar-Reduced 25 mg/ml Suspension Nu-Amoxi 25 mg/ml Suspension Pms-Amoxicillin 25 mg/ml Suspension Apo-Amoxi 50 mg/ml Suspension
Novamoxin 50 mg/ml Suspension Novamoxin Sugar-Reduced 50 mg/ml Suspension Nu-Amoxi 50 mg/ml Suspension Pms-Amoxicillin 50 mg/ml Suspension
Apo-Amoxi 250 mg Capsule Mylan-Amoxillin 250 mg Capsule Novamoxin 250 mg Capsule Nu-Amoxi 250 mg Capsule
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Synonyms of Amoxicillin:

AMC, Amoxicilina [INN-Spanish], Amoxicillin Anhydrous, Amoxicillin Trihydrate, Amoxicilline [INN-French], Amoxicillinum [INN-Latin], Amoxycillin, Amoxycillin Trihydrate, D-Amoxicillin, P-Hydroxyampicillin

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