Tags: Tetracycline

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Tetracycline is authorised in the world under the following brand names: Abramycin, Abricycline, Achromycin, Achromycin V, Actisite, Agromicina, Ambramicina, Ambramycin, Amycin, Bio-Tetra, Biocycline, Bristaciclin, Bristaciclina, Bristacycline, Cefracycline, Ciclibion, Copharlan, Criseociclina, Cyclopar, Cytome, Democracin, Deschlorobiomycin, Dumocyclin, Enterocycline, Hostacyclin, Lexacycline, Limecycline, Liquamycin, Medocycline, Mericycline, Micycline, Neocycline, Oletetrin, Omegamycin, Orlycycline, Panmycin, Polycycline, Polyotic, Purocyclina, Resteclin, Retet, Robitet, Roviciclina, SK-Tetracycline, Solvocin, Sumycin, TAC, Tetra-CO, Tetrabon, Tetrachel, Tetracycl, Tetracycline II, Tetracyn, Tetradecin, Tetrafil, Tetramed, Tetraverine, Tetrex, Topicycline, Tsiklomistsin, Tsiklomitsin, Veracin, Vetacyclinum.

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Pathogenic Amebas

ENTAMOEBA HISTOLYTICA & ENTAMOEBA DISPAR Essentials of Diagnosis Patient living in or having traveled to endemic area increases risk. Frequent loose stools with blood and mucus. Demonstration of cyst or trophozoite on stool wet mount or in biopsy specimen. Serology positive within 7-10 days of infection, may remain positive for years after infection resolved. Monoclonal antibodies and polymerase chain reaction emerging; may help differentiate E histolytica and E dispar. General Considerations Epidemiology There are numerous distinct species of ameba within the genus Entamoeba, and the majority of these do not cause disease in humans. E histolytica is a pathogenic species that is capable of causing disease, such as colitis or liver […]

Amebic Liver Abscess

Clinical Findings Signs and Symptoms Amebic liver abscess is the most common extraintestinal manifestation of amebiasis. Patients may note right-upper-quadrant pain that is either dull or pleuritic in nature. Often pain is referred to the right shoulder. Less than 50% of patients have an enlarged liver. In the acute setting, patients typically manifest fever. If symptoms have been present for > 2 weeks, fever is present in less than half of patients. Respiratory symptoms, such as cough, can occur even in the absence of pulmonary disease and may be the only complaint. In the subacute setting, weight loss is common. Diarrhea is found in less than one-third of patients with amebic […]

Non-falciparum Malaria (P Vivax, P Ovale, P Malariae)

Clinical Findings Signs and Symptoms Patients with nonfalciparum malaria invariably develop fever and chills that may become cyclic. Initially, patients experience chills, which are followed by fever (Box 1). Patients with malaria often manifest many nonspecific symptoms such as weakness, malaise, headache, and myalgias. As the disease progresses, signs of anemia, such as pale conjunctiva, may be seen. Splenomegaly and mild hepatomegaly may also be present. After hours of fever, defervescence occurs with marked diaphoresis. Patients are weakened and exhausted from the severity of the disease. In established infections caused by P vivax and P ovale, a periodicity may occur approximately every 48 h. P vivax and P ovale infections are […]

Fever & Bacteremia/Trench Fever/Endocarditis

The four Bartonella species that are pathogenic for humans are capable of causing sustained or relapsing bacteremia accompanied by only fever (Table 1). All except B bacilliformis also cause endocarditis. After B quintana enters the body through broken skin from the excreta of the infected human body louse (Pediculus humanus), there is an incubation period of between 5 and 20 days before the onset of trench fever. Patients complain of fever, myalgias, malaise, headache, bone pain — particularly of the legs, and a transient macular rash. Usually the illness continues for 4-6 weeks. Sustained or recurrent bacteremia is common, with or without symptoms. The form of trench fever described in the […]

Ehrlichia Infection (Ehrlichiosis)

Essentials of Diagnosis Key symptoms and signs: abrupt onset of high fever, headache, myalgias, chills 8-9 days after tick bite; rash (36% of human monocytic ehrlichiosis [HME] patients; only 2% of human granulocytic ehrlichiosis [HGE] patients); central nervous system involvement (20-25% of patients). Predisposing factors: tick and rural exposure (April through September). Presentation: most present as flu-like illness. Key laboratory features: thrombocytopenia, leukopenia, and elevated liver transaminases. Diagnosis: confirmed by a fourfold or greater rise in titers with an IFA. General Considerations Human ehrlichiosis was first recognized in the United States in 1986 as a life threatening tick-borne illness similar to Rocky Mountain spotted fever (RMSF), but with a much lower […]

Coxiella, Ehrlichia, & Rickettsia

Coxiella, Ehrlichia, and Rickettsia spp. are small, obligate intracellular bacteria that usually cause disease when they accidentally encounter a human host. Once inside a host cell, Coxiella and Ehrlichia spp. remain within a vacuole where they progress through distinct developmental stages; in contrast, the Rickettsia spp. escape the endocytic vacuole and replicate within the host cell cytoplasm. Ehrlichia and Rickettsia spp. are transmitted by arthropod vectors. COXIELLA BURNETII INFECTION (Q FEVER) Essentials of Diagnosis Acute Infection Key symptoms and signs: fever, severe headache, myalgias, arthralgias, retrobulbar pain, cough; possible pneumonitis and hepatitis on examination. Predisposing factors: occupation as a dairy farmer, abattoir worker, or veterinarian; exposure to parturient or newborn animals, […]

Chlamydia

General Considerations Chlamydia trachomatis, Chlamydia psittaci, and Chlamydia pneumoniae are among the most prevalent microbial pathogens in humans worldwide. C trachomatis is responsible for a variety of sexually transmitted disease (STD) syndromes in both sexes. In addition, certain serotypes of C trachomatis are responsible for trachoma, the most common infectious cause of blindness in humans. C psittaci is a zoonotic pathogen associated with atypical pneumonia. C pneumoniae infects approximately one-half of the world's human population and is a cause of upper and lower respiratory tract disease. It has also been associated with atherosclerotic cardiovascular disease. Epidemiology In the United States, genital infections by C trachomatis serovars D through K occur frequently […]

Chlamydia Psittaci Infections

Essentials of Diagnosis History of contact with birds. Positive C psittaci-specific microimmunofluorescence serologies. Positive complement fixation titers (not species specific). Clinical Findings Signs and Symptoms Pneumonia, pericarditis, myocarditis, and endocarditis have been attributed to C psittaci infection (psittacosis or ornithosis) (Box 5). The incubation period for the pneumonia is usually 1-2 weeks. Its onset is gradual with body temperature increasing over a period of 5-7 days; however, there are cases in which the onset is sudden with rigors and temperatures as high as 104 °F. Headache is a salient and important symptom; it can be severe and incapacitating. Cough is usually nonproductive and hacking; however, on occasion a mucoid sputum or […]

Chlamydia Trachomatis Infections

Essentials of Diagnosis Typical intracytoplasmic inclusions in Giemsa-stained cell scrapings from the conjunctiva. Ligase chain reaction (LCR) or polymerase chain reaction (PCR) in first-void urine. Positive culture in McCoy or HeLa cells of body fluids or secretions. Positive microimmunofluorescence serology for suspected cases of lymphogranuloma venereum and infants with pneumonia. Complement fixation titer of 1:64 or greater in patients with presumed lymphogranuloma venereum. Clinical Syndromes C trachomatis is associated with urethritis, proctitis, conjunctivitis, and arthritis in women and men; epididymitis in men; and mucopurulent cervicitis (MPC), acute salpingitis, bartholinitis, and the Fitz-Hugh and Curtis syndrome in women (Box 1). C trachomatis and Neisseria gonorrhoeae (see site) coinfections are common in women […]

Mycoplasma & Ureaplasma

Mycoplasma and Ureaplasma species (mycoplasmas) are ubiquitous in nature and are commonly found in plants, animals, and humans. These bacteria contain the smallest amount of double-stranded DNA that is capable of producing a free-living microorganism; they measure between 0.15 and 0.3 um in diameter and = 2 um in length. They are believed to have evolved from a putative common ancestor of the gram-positive bacteria by a process of genome reduction and adoption of a dependent, parasitic life style. Mycoplasma and Ureaplasma spp. lack a cell wall. Therefore, they cannot be visualized with the Gram stain and are not susceptible to antibiotics that act on cell wall synthesis (eg, penicillins and […]

Dosage forms of Tetracycline:
Tetracycline powder Tetracycline hcl powder Apo-Tetra 250 mg Capsule Tetracycline HCl 250 mg capsule
Tetracycline HCl 500 mg capsule      

Synonyms of Tetracycline:

Anhydrotetracycline, TC, Tetracycline HCl

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Therapeutic classes of Tetracycline:

Anti-Bacterial Agents, Antiprotozoals, Protein Synthesis Inhibitors, Tetracyclines

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